CONDITIONS

Osteoarthritis and Obesity

Obesity is the strongest modifiable risk factor for knee osteoarthritis — every 5 kg of weight gain increases risk by 36%, and even modest weight loss can relieve joint pain.

Osteoarthritis is a condition where the cushioning cartilage in your joints wears down, causing pain and stiffness. Carrying extra weight puts more pressure on weight-bearing joints like knees and hips, which can make osteoarthritis worse and speed up joint damage.

Osteoarthritis (OA) is a degenerative joint disease characterised by progressive articular cartilage loss, subchondral bone remodelling, and synovial inflammation. Obesity is the strongest modifiable risk factor for knee OA, with each 5 kg of weight gain increasing the risk by 36%. Adipose tissue-derived pro-inflammatory adipokines (leptin, resistin) contribute to both mechanical and systemic inflammatory joint degradation.

Even modest weight loss of 5–10% can significantly reduce joint pain and slow OA progression. A structured medical weight management programme addresses both the mechanical load and the inflammatory component, offering dual symptom relief and disease-modifying benefits.

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Medical Disclaimer

This library is for general education and does not replace individual assessment by a qualified healthcare professional. Always consult a doctor for medical advice, diagnosis, or treatment.

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