Patient-Friendly Explanation

Alpha-blockers are medicines used for high blood pressure and prostate problems. They relax blood vessels, which can cause dizziness when you stand up, and they can shift a little fluid and weight. They rarely cause real fat gain, but fluid retention can still show on the scale.

Clinical Definition

Alpha-1 antagonists such as doxazosin, prazosin and terazosin produce vasodilation and orthostatic hypotension. In hypertension trials they are associated with modest weight gain relative to thiazides, largely through fluid retention and compensatory tachycardia. Because they are sedating and can cause first-dose syncope, they may also reduce habitual physical activity.

Why It Matters

When several blood-pressure medicines are taken together, the scale can move with no change in body fat at all. NuLifeCare Singapore reviews every prescription before adjusting a weight plan.