Patient-Friendly Explanation

Cholecystokinin, or CCK, is a hormone that your small intestine releases when you eat, especially when you consume protein and fats. It slows down stomach emptying and tells your brain you have had enough to eat.

Clinical Definition

Cholecystokinin is a peptide hormone secreted by I-cells in the duodenal and jejunal mucosa in response to luminal nutrients, particularly long-chain fatty acids and amino acids. CCK acts via CCK-A receptors on vagal afferent nerves to induce satiety, while also stimulating gallbladder contraction and pancreatic enzyme secretion.

Why It Matters

CCK is one of the body’s most immediate satiety signals, explaining why meals rich in protein and healthy fats tend to be more filling. NuLifeCare Singapore incorporates macronutrient-balanced meal planning into its weight management programme to naturally optimise CCK release and support appetite control.