CONDITIONS

Cushing’s Syndrome

A hormonal disorder caused by excess cortisol that leads to weight gain, particularly in the face and trunk.

Cushing's syndrome occurs when the body is exposed to too much cortisol, a stress hormone, over a long period of time. This can lead to weight gain, especially around the face and abdomen, along with high blood pressure, muscle weakness, and easy bruising.

Cushing's syndrome results from chronic glucocorticoid excess — either endogenous (ACTH-secreting pituitary adenoma or adrenal tumour) or exogenous (prolonged corticosteroid use). Characteristic features include centripetal obesity, moon facies, dorsal cervical fat pad, proximal myopathy, and insulin resistance secondary to cortisol-driven gluconeogenesis and lipolysis.

If you have unexplained weight gain with other symptoms like a rounded face, thinning skin, or muscle weakness, a comprehensive medical evaluation at NuLifeCare Singapore can help identify whether an underlying condition like Cushing's syndrome is contributing to your weight changes.

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Medical Disclaimer

This library is for general education and does not replace individual assessment by a qualified healthcare professional. Always consult a doctor for medical advice, diagnosis, or treatment.

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