Patient-Friendly Explanation

Mazdutide is an investigational medication that works on two gut hormones — GLP-1 and glucagon — to reduce appetite and help the body burn more energy. It is currently in clinical trials and has shown promising weight loss results.

Clinical Definition

Mazdutide is a unimolecular dual agonist of the glucagon-like peptide-1 (GLP-1) and glucagon receptors. By co-activating GLP-1R (appetite suppression, delayed gastric emptying) and GCGR (increased energy expenditure, lipolysis, hepatic fat oxidation), it targets both energy intake and expenditure — a dual mechanism that may produce superior weight loss compared to GLP-1 mono-agonists.

Why It Matters

Dual and triple agonists represent the next generation of obesity pharmacotherapy. Dr. Joseph Wang stays current with emerging treatments to offer patients at NuLifeCare Singapore the most appropriate, evidence-based options.