MEDICATIONS

Metformin

A diabetes medication that also supports weight loss by improving insulin sensitivity and reducing appetite.

Metformin is a widely prescribed medication primarily used to treat type 2 diabetes by lowering blood sugar levels. It also has a modest weight loss effect — many patients lose 2-3 kg — because it reduces appetite and improves how the body responds to insulin, making it easier to burn stored fat.

Metformin is a biguanide antihyperglycaemic agent that reduces hepatic gluconeogenesis, increases peripheral insulin sensitivity, and decreases intestinal glucose absorption. Its weight-modulating effects are thought to stem from AMPK activation, altered gut microbiota, and increased GLP-1 secretion. While not primarily a weight loss drug, meta-analyses show a mean weight reduction of 2.1 kg versus placebo in overweight individuals.

Metformin is often the first-line medication for patients with insulin resistance or prediabetes who are struggling with weight. At NuLifeCare, Dr. Joseph Wang may prescribe metformin as part of a comprehensive weight management plan for patients who have difficulty losing weight due to underlying insulin resistance.

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Medical Disclaimer

This library is for general education and does not replace individual assessment by a qualified healthcare professional. Always consult a doctor for medical advice, diagnosis, or treatment.

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