Prader-Willi Syndrome
A rare genetic disorder causing constant hunger, slow metabolism, and reduced muscle tone, often leading to severe obesity from early childhood.
Patient-Friendly Explanation
Prader-Willi Syndrome is a rare genetic condition present from birth that causes an unrelenting feeling of hunger. People with this syndrome never feel full, which combined with a naturally slow metabolism, makes weight management extremely challenging from a very young age.
Clinical Definition
Prader-Willi Syndrome (PWS) results from the loss of function of specific genes on chromosome 15 (paternal 15q11-q13). It is characterised by hypotonia in infancy, hypogonadism, cognitive impairment, and hyperphagia leading to morbid obesity. Growth hormone deficiency is common, and patients have reduced lean body mass and resting energy expenditure.
Why It Matters
While PWS requires specialised multidisciplinary care, many weight management principles overlap. At NuLifeCare, we understand that obesity has diverse causes — from genetics to lifestyle — and we tailor every treatment plan accordingly. If you struggle with weight despite your best efforts, a medical evaluation can uncover underlying factors.
This library is for general education and does not replace individual assessment by a qualified healthcare professional. Always consult a doctor for medical advice, diagnosis, or treatment.
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